USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: MIP_HUMAN USC-OGP 2-DE database:  MIP_HUMAN MIP_HUMAN General information about the entry View entry in simple text format Entry name MIP_HUMAN Primary accession number P30301 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Lens fiber major intrinsic protein; AltName: Full=Aquaporin-0; AltName: Full=MIP26; Short=MP26;. Gene name Name=MIP Synonyms=AQP0 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0348: pI=5.65; Mw=54664 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0654: pI=5.66; Mw=55779 Cross-references UniProtKB/Swiss-Prot P30301; MIP_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name MIP_HUMAN Primary accession number P30301 Secondary accession number(s) Q17R41 Sequence was last modified on  April 1, 1993 (version 1) Annotations were last modified on  March 15, 2017 (version 165) Name and origin of the protein Description RecName: Full=Lens fiber major intrinsic protein; AltName: Full=Aquaporin-0; AltName: Full=MIP26; Short=MP26; Gene name Name=MIP Synonyms=AQP0 Encoded on Name=MIP; Synonyms=AQP0 Keywords Cataract; Cell junction; Cell membrane; Complete proteome; Disease mutation; Eye lens protein; Gap junction; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome; Repeat; Sensory transduction; Transmembrane; Transmembrane helix; Transport; Vision. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U36308; AAC02794.2; -; Genomic_DNA EMBL AC024884; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC074913; AAH74913.1; -; mRNA EMBL BC117474; AAI17475.1; -; mRNA CCDS CCDS8919.1; -; . PIR A55279; A55279; . RefSeq NP_036196.1; NM_012064.3; . UniGene Hs.574026; -; . ProteinModelPortal P30301; -; . SMR P30301; -; . BioGrid 110430; 5; . IntAct P30301; 5; . MINT MINT-8415310; -; . STRING 9606.ENSP00000257979; -; . iPTMnet P30301; -; . PhosphoSitePlus P30301; -; . BioMuta MIP; -; . DMDM 266537; -; . OGP P30301; -; . PaxDb P30301; -; . PeptideAtlas P30301; -; . PRIDE P30301; -; . DNASU 4284; -; . Ensembl ENST00000257979; ENSP00000257979; ENSG00000135517; . GeneID 4284; -; . KEGG hsa:4284; -; . UCSC uc001slh.4; human; . CTD 4284; -; . DisGeNET 4284; -; . GeneCards MIP; -; . HGNC HGNC:7103; MIP; . HPA HPA014940; -; . MalaCards MIP; -; . MIM 154050; gene; . MIM 615274; phenotype; . neXtProt NX_P30301; -; . OpenTargets ENSG00000135517; -; . Orphanet 98985; Cataract with Y-shaped suture opacities; . Orphanet 98989; Cerulean cataract; . Orphanet 98991; Nuclear cataract; . Orphanet 98994; Total congenital cataract; . Orphanet 98995; Zonular cataract; . PharmGKB PA30821; -; . eggNOG KOG0223; Eukaryota; . eggNOG COG0580; LUCA; . GeneTree ENSGT00760000119223; -; . HOGENOM HOG000288286; -; . HOVERGEN HBG000312; -; . InParanoid P30301; -; . KO K09863; -; . OMA MWELRST; -; . OrthoDB EOG091G166T; -; . PhylomeDB P30301; -; . TreeFam TF312940; -; . Reactome R-HSA-432047; Passive transport by Aquaporins; . SIGNOR P30301; -; . GeneWiki MIP_(gene); -; . GenomeRNAi 4284; -; . PMAP-CutDB P30301; -; . PRO PR:P30301; -; . Proteomes UP000005640; Chromosome 12; . Bgee ENSG00000135517; -; . CleanEx HS_MIP; -; . Genevisible P30301; HS; . GO GO:0016324; C:apical plasma membrane; IBA:GO_Central; . GO GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB; . GO GO:0005921; C:gap junction; IEA:UniProtKB-SubCell; . GO GO:0005887; C:integral component of plasma membrane; ISS:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0005516; F:calmodulin binding; ISS:UniProtKB; . GO GO:0005212; F:structural constituent of eye lens; IEA:UniProtKB-KW; . GO GO:0015250; F:water channel activity; IDA:UniProtKB; . GO GO:1990349; P:gap junction-mediated intercellular transport; IDA:UniProtKB; . GO GO:0034220; P:ion transmembrane transport; IBA:GO_Central; . GO GO:0002088; P:lens development in camera-type eye; IEA:Ensembl; . GO GO:0045785; P:positive regulation of cell adhesion; IDA:UniProtKB; . GO GO:0051289; P:protein homotetramerization; IDA:UniProtKB; . GO GO:0050896; P:response to stimulus; IEA:UniProtKB-KW; . GO GO:0007601; P:visual perception; IEA:UniProtKB-KW; . GO GO:0006833; P:water transport; ISS:UniProtKB; . CDD cd00333; MIP; 1; . Gene3D 1.20.1080.10; -; 1; . InterPro IPR023271; Aquaporin-like; . InterPro IPR034294; Aquaporin_transptr; . InterPro IPR000425; MIP; . InterPro IPR022357; MIP_CS; . PANTHER PTHR19139; PTHR19139; 1; . Pfam PF00230; MIP; 1; . PRINTS PR00783; MINTRINSICP; . SUPFAM SSF81338; SSF81338; 1; . TIGRFAMs TIGR00861; MIP; 1; . PROSITE PS00221; MIP; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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